Two beautiful women who live in the same apartment building each have a shocking story to tell. On the first floor lives Silvia Resino (Alexandra Paulhiac), who has three psychotic admirers while on the second floor, RoseMarie Curtis (Sasha Graham) is descending into madness after joining an insane acting school.

Jake, a lycanthrope, on the run from the authorities in an apocalyptic New York City, must make his way past helicopters, police, subterranean mutants, bounty hunters and even a spy in his midst in order to discover exactly what his evil werewolf brother is up to and resolve the bad blood that flows between them...