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Two men wake up to find themselves shackled in a grimy, abandoned bathroom. As they struggle to comprehend their predicament, they discover a disturbing tape left behind by the sadistic mastermind known as Jigsaw. With a chilling voice and cryptic instructions, Jigsaw informs them that they must partake in a gruesome game in order to secure their freedom.

Jigsaw has disappeared. Along with his new apprentice Amanda, the puppet-master behind the cruel, intricate games that have terrified a community and baffled police has once again eluded capture and vanished. While city detectives scramble to locate him, Doctor Lynn Denlon and Jeff Reinhart are unaware that they are about to become the latest pawns on his vicious chessboard.

As a deadly battle rages over Jigsaw's brutal legacy, a group of Jigsaw survivors gathers to seek the support of self-help guru and fellow survivor Bobby Dagen, a man whose own dark secrets unleash a new wave of terror.

Law enforcement finds itself chasing the ghost of a man dead for over a decade, embroiled in a diabolical new game that's only just begun.