Set in Springfield, the average American town, the show focuses on the antics and everyday adventures of the Simpson family; Homer, Marge, Bart, Lisa and Maggie, as well as a virtual cast of thousands. Since the beginning, the series has been a pop culture icon, attracting hundreds of celebrities to guest star. The show has also made name for itself in its fearless satirical take on politics, media and American life in general.

Seth Meyers, who is "Saturday Night Live's" longest serving anchor on the show's wildly popular "Weekend Update," takes over as host of NBC's "Late Night" — home to A-list celebrity guests, memorable comedy and the best in musical talent. As the Emmy Award-winning head writer for "SNL," Meyers has established a reputation for sharp wit and perfectly timed comedy, and has gained fame for his spot-on jokes and satire. Meyers takes his departure from "SNL" to his new post at "Late Night," as Jimmy Fallon moves to "The Tonight Show".

Six young people from New York City, on their own and struggling to survive in the real world, find the companionship, comfort and support they get from each other to be the perfect antidote to the pressures of life.

The series focuses on an eccentric motley crew that is the Smith family and their three housemates: Father, husband, and breadwinner Stan Smith; his better half housewife, Francine Smith; their college-aged daughter, Hayley Smith; and their high-school-aged son, Steve Smith. Outside of the Smith family, there are three additional main characters, including Hayley's boyfriend turned husband, Jeff Fischer; the family's man-in-a-goldfish-body pet, Klaus; and most notably the family's zany alien, Roger, who is "full of masquerades, brazenness, and shocking antics."

Young Finn and his shape-shifting dog buddy, Jake, go on a series of surreal adventures as they journey through the postapocalyptic Land of Ooo.

Bob's Burgers follows a third-generation restaurateur, Bob, as he runs Bob's Burgers with the help of his wife and their three kids. Bob and his quirky family have big ideas about burgers, but fall short on service and sophistication. Despite the greasy counters, lousy location and a dearth of customers, Bob and his family are determined to make Bob's Burgers "grand re-re-re-opening" a success.

A stand-up comedian and his three offbeat friends weather the pitfalls and payoffs of life in New York City in the '90s. It's a show about nothing.

A late night television talk show hosted by Conan O'Brien.

After accidentally creating a new multiverse, comic book store owner Stuart Bloom must locate a quantum-interference device to restore reality.

Physicists Leonard and Sheldon find their nerd-centric social circle with pals Howard and Raj expanding when aspiring actress Penny moves in next door.

After the fall of the Galactic Empire, lawlessness has spread throughout the galaxy. A lone gunfighter makes his way through the outer reaches, earning his keep as a bounty hunter.

Jessica Day is an offbeat and adorable girl in her late 20s who, after a bad breakup, moves in with three single guys. Goofy, positive, vulnerable and honest to a fault, Jess has faith in people, even when she shouldn't. Although she's dorky and awkward, she's comfortable in her own skin. More prone to friendships with women, she's not used to hanging with the boys—especially at home.

A self-loathing, alcoholic writer attempts to repair his damaged relationships with his daughter and her mother while combating sex addiction, a budding drug problem, and the seeming inability to avoid making bad decisions.

Follow the lives of a group of students at what is possibly the world’s worst community college in the fictional locale of Greendale, Colorado.

The adventures of four penguins—Skipper, Kowalski, Private, and Rico, who perform various commando-like missions to protect their home in the Central Park Zoo. The penguins often have to deal with problems caused, or made worse, by their zoo neighbors, King Julien XIII (a ring-tailed lemur), Maurice (an aye-aye), and Mort (a mouse lemur).

If there's danger or trouble, Kim Possible is there on the double to save the world from villains... and still make it home in time for cheerleading practice! Luckily, Kim has her sidekick Ron Stoppable and his pet naked mole-rat Rufus by her side.

A young boy takes his mother's place in a group of gemstone-based beings, and must learn to control his powers.

Intergalactic warrior Star Butterfly arrives on Earth to live with the Diaz family. She continues to battle villains throughout the universe and high school, mainly to protect her extremely powerful wand, an object that still confuses her.

Chris Hardwick will lead three celebrity contestants down the ultimate internet wormhole. Culling from the darkest recesses of social media, they will compete to determine who has the funniest take on the day's pop culture.

Stepping into the late-late slot vacated by David Letterman, Conan O'Brien stars in a show that far outdoes its competition in sheer strangeness. Along with the celebrity interviews and musical numbers typical of late-night talk shows, this program make frequent use of odd walk-on characters and frequent "visits" from celebrity guests.